AODB stores existing antioxidants involving 56,666 small molecules, 1,480 peptides, and 998 proteins, as well as their related data including 7,781 antioxidant assay records, 59,144 physicochemical and 56,666 ADMET properties, 2D and 3D structural information, and 6802 literature citation information. AODB aims to provide researchers with a free database of antioxidants to promote antioxidant research and development.

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Small molecule antioxidant assay items can be attributed to the following seven categories, depending on the types of reactions involved in their assays:

1. Hydrogen atom transfer (HAT) reaction-based assay, including ORAC, TRAP, β-Carotene bleaching, Crocin bleaching assays, Inhibition of linoleic acid oxidation, chemiluminescence assay, TOSCA and others.
2. Electron transfer (ET) reaction-based assay, including ABTS, DPPH, FCR, TEAC, FRAP, DMPD, CUPRAC and others.
3. The inhibition of lipid peroxidation based assay, including TBARS, FOX, Lipid peroxidation inhibition assay, and others.
4. Assay based on antioxidant /pro-oxidant enzymes, including GSt, SOD, CAT, GSH, LOX, xanthine oxidase, and others.
5. Assay via targeting Nrf2-antioxidant response element signaling pathway.
6. Cell-based bioassays.
7. Superoxide radical scavenging activity, hydroxyl radical scavenging activity, nitric oxide scavenging, FTC, metal chelating activity, xanthine oxidase method, phosphomolybdenum method, RP, peroxynitrite radical scavenging activity, hydrogen peroxide scavenging activity, singlet oxygen scavenging, activity and others.